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			</style>[an error occurred while processing this directive]<div class="content-width"><ol class="breadcrumb text-uppercase"><li><a href="/">Home</a></li><li><a href="/aboutus/">About Us</a></li><li><a href="/people/">People</a></li><li><a href="/people/students.html">Students</a></li><li><a href="/people/ChonLok.Lei"><span itemprop="name">Chon Lok Lei</span></a></li><li class="active">Publications</li></ol></div><!-- MOBILE NAVIGATION --><div class="content-width space-below mobile-menu-placeholder visible-xs visible-sm"></div><!-- COLUMNS --><div class="container-fluid content-width"><div class="row"><div class="col-xs-12 col-md-9 col-md-push-3" id="maincontent"><!-- CONTENT (Column 2) --><div class="page-title"><h1>Chon Lok Lei : Publications
</h1></div><div role="toolbar" class="btn-toolbar"><div class="btn-group"><a href="/people/publications/date/ChonLok.Lei.html" aria-hidden="true" type="button" class="btn btn-oxford-blue"><span class="glyphicon glyphicon-sort-by-attributes"></span> By date</a><a href="/people/publications/title/ChonLok.Lei.html" aria-hidden="true" type="button" class="btn btn-default"><span class="glyphicon glyphicon-sort-by-attributes"></span> By title</a><a href="/people/publications/type/ChonLok.Lei.html" aria-hidden="true" type="button" class="btn btn-default"><span class="glyphicon glyphicon-sort-by-attributes"></span> By type</a><a href="/people/publications/bibtex/ChonLok.Lei.html" aria-hidden="true" type="button" class="btn btn-default"><span class="glyphicon glyphicon-file"></span> BibTex</a></div></div><p></p><ul class="list-unbulleted list-unbulleted-spaced"><li>
	
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	<p class="publicationTitle"> <strong>
            Model Evidence with Fast Tree Based Quadrature </strong> </p>
	    <p class="publicationAuthors"> <em> Thomas Foster&#x201a; Chon Lok Lei&#x201a; Martin Robinson&#x201a; David Gavaghan and Ben Lambert  </em> </p>
	
	<p class="publicationDetails"> 
        In <em>arXiv preprint arXiv:2005.11300</em>.
        2020.
        </p>
	
        		<p class="publicationlinks"> <a
        
            		href="/publications/publication14113-abstract.html">
			Details <span class="sr-only" > about <em> Model Evidence with Fast Tree Based Quadrature  </em></span> </a> |
			<a href="/publications/publication14113.bib">
			BibTeX  <span class="sr-only" > data for <em> Model Evidence with Fast Tree Based Quadrature  </em></span>   </a>
			
			
					| <a href="https://arxiv.org/abs/2005.11300"> Link <span class="sr-only" > to <em> Model Evidence with Fast Tree Based Quadrature  </em></span> </a>
  				
		
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	<p class="publicationTitle"> <strong>
            Accounting for variability in ion current recordings using a mathematical model of artefacts in voltage&#x2212;clamp experiments </strong> </p>
	    <p class="publicationAuthors"> <em> Chon Lok Lei&#x201a; Michael Clerx&#x201a; Dominic G. Whittaker&#x201a; David J. Gavaghan&#x201a; Teun P. de Boer and Gary R. Mirams  </em> </p>
	
	<p class="publicationDetails"> 
        In <em>Philosophical Transactions of the Royal Society A: Mathematical&#x201a; Physical and Engineering Sciences</em>.
        
            Vol. 378.
        
            No. 2173.
        
                Pages 20190348.
            2020.
        </p>
	
        		<p class="publicationlinks"> <a
        
            		href="/publications/publication14112-abstract.html">
			Details <span class="sr-only" > about <em> Accounting for variability in ion current recordings using a mathematical model of artefacts in voltage&#x2212;clamp experiments  </em></span> </a> |
			<a href="/publications/publication14112.bib">
			BibTeX  <span class="sr-only" > data for <em> Accounting for variability in ion current recordings using a mathematical model of artefacts in voltage&#x2212;clamp experiments  </em></span>   </a>
			
			 | <a
		href="http://dx.doi.org/10.1098/rsta.2019.0348">
		DOI (10.1098/rsta.2019.0348)
		</a> 
					| <a href="https://royalsocietypublishing.org/doi/abs/10.1098/rsta.2019.0348"> Link <span class="sr-only" > to <em> Accounting for variability in ion current recordings using a mathematical model of artefacts in voltage&#x2212;clamp experiments  </em></span> </a>
  				
		
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	<p class="publicationTitle"> <strong>
            Considering discrepancy when calibrating a mechanistic electrophysiology model </strong> </p>
	    <p class="publicationAuthors"> <em> Chon Lok Lei&#x201a; Sanmitra Ghosh&#x201a; Dominic G. Whittaker&#x201a; Yasser Aboelkassem&#x201a; Kylie A. Beattie&#x201a; Chris D. Cantwell&#x201a; Tammo Delhaas&#x201a; Charles Houston&#x201a; Gustavo Montes Novaes&#x201a; Alexander V. Panfilov&#x201a; Pras Pathmanathan&#x201a; Marina Riabiz&#x201a; Rodrigo Weber dos Santos&#x201a; John Walmsley&#x201a; Keith Worden&#x201a; Gary R. Mirams and Richard D. Wilkinson  </em> </p>
	
	<p class="publicationDetails"> 
        In <em>Philosophical Transactions of the Royal Society A: Mathematical&#x201a; Physical and Engineering Sciences</em>.
        
            Vol. 378.
        
            No. 2173.
        
                Pages 20190349.
            2020.
        </p>
	
        		<p class="publicationlinks"> <a
        
            		href="/publications/publication14111-abstract.html">
			Details <span class="sr-only" > about <em> Considering discrepancy when calibrating a mechanistic electrophysiology model  </em></span> </a> |
			<a href="/publications/publication14111.bib">
			BibTeX  <span class="sr-only" > data for <em> Considering discrepancy when calibrating a mechanistic electrophysiology model  </em></span>   </a>
			
			 | <a
		href="http://dx.doi.org/10.1098/rsta.2019.0349">
		DOI (10.1098/rsta.2019.0349)
		</a> 
					| <a href="https://royalsocietypublishing.org/doi/abs/10.1098/rsta.2019.0349"> Link <span class="sr-only" > to <em> Considering discrepancy when calibrating a mechanistic electrophysiology model  </em></span> </a>
  				
		
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	<p class="publicationTitle"> <strong>
            An audit of uncertainty in multi&#x2212;scale cardiac electrophysiology models </strong> </p>
	    <p class="publicationAuthors"> <em> Richard H. Clayton&#x201a; Yasser Aboelkassem&#x201a; Chris D. Cantwell&#x201a; Cesare Corrado&#x201a; Tammo Delhaas&#x201a; Wouter Huberts&#x201a; Chon Lok Lei&#x201a; Haibo Ni&#x201a; Alexander V. Panfilov&#x201a; Caroline Roney and Rodrigo Weber dos Santos  </em> </p>
	
	<p class="publicationDetails"> 
        In <em>Philosophical Transactions of the Royal Society A: Mathematical&#x201a; Physical and Engineering Sciences</em>.
        
            Vol. 378.
        
            No. 2173.
        
                Pages 20190335.
            2020.
        </p>
	
        		<p class="publicationlinks"> <a
        
            		href="/publications/publication14110-abstract.html">
			Details <span class="sr-only" > about <em> An audit of uncertainty in multi&#x2212;scale cardiac electrophysiology models  </em></span> </a> |
			<a href="/publications/publication14110.bib">
			BibTeX  <span class="sr-only" > data for <em> An audit of uncertainty in multi&#x2212;scale cardiac electrophysiology models  </em></span>   </a>
			
			 | <a
		href="http://dx.doi.org/10.1098/rsta.2019.0335">
		DOI (10.1098/rsta.2019.0335)
		</a> 
					| <a href="https://royalsocietypublishing.org/doi/abs/10.1098/rsta.2019.0335"> Link <span class="sr-only" > to <em> An audit of uncertainty in multi&#x2212;scale cardiac electrophysiology models  </em></span> </a>
  				
		
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	<p class="publicationTitle"> <strong>
            Considering discrepancy when calibrating a mechanistic electrophysiology model </strong> </p>
	    <p class="publicationAuthors"> <em> Chon Lok Lei&#x201a; Sanmitra Ghosh&#x201a; Dominic G Whittaker&#x201a; Yasser Aboelkassem&#x201a; Kylie A Beattie&#x201a; Chris D Cantwell&#x201a; Tammo Delhaas&#x201a; Charles Houston&#x201a; Gustavo Montes Novaes&#x201a; Alexander V Panfilov and others  </em> </p>
	
	<p class="publicationDetails"> 
        In <em>arXiv preprint arXiv:2001.04230</em>.
        2020.
        </p>
	
        		<p class="publicationlinks"> <a
        
            		href="/publications/publication14102-abstract.html">
			Details <span class="sr-only" > about <em> Considering discrepancy when calibrating a mechanistic electrophysiology model  </em></span> </a> |
			<a href="/publications/publication14102.bib">
			BibTeX  <span class="sr-only" > data for <em> Considering discrepancy when calibrating a mechanistic electrophysiology model  </em></span>   </a>
			
			
					| <a href="https://arxiv.org/abs/2001.04230"> Link <span class="sr-only" > to <em> Considering discrepancy when calibrating a mechanistic electrophysiology model  </em></span> </a>
  				
		
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	<p class="publicationTitle"> <strong>
            Calibration of ionic and cellular cardiac electrophysiology models </strong> </p>
	    <p class="publicationAuthors"> <em> Dominic G Whittaker&#x201a; Michael Clerx&#x201a; Chon Lok Lei&#x201a; David J Christini and Gary R Mirams  </em> </p>
	
	<p class="publicationDetails"> 
        In <em>Wiley Interdisciplinary Reviews: Systems Biology and Medicine</em>.
        
                Pages e1482.
            2020.
        </p>
	
        		<p class="publicationlinks"> <a
        
            		href="/publications/publication14100-abstract.html">
			Details <span class="sr-only" > about <em> Calibration of ionic and cellular cardiac electrophysiology models  </em></span> </a> |
			<a href="/publications/publication14100.bib">
			BibTeX  <span class="sr-only" > data for <em> Calibration of ionic and cellular cardiac electrophysiology models  </em></span>   </a>
			
			 | <a
		href="http://dx.doi.org/10.1002/wsbm.1482">
		DOI (10.1002/wsbm.1482)
		</a> 
					| <a href="https://doi.org/10.1002/wsbm.1482"> Link <span class="sr-only" > to <em> Calibration of ionic and cellular cardiac electrophysiology models  </em></span> </a>
  				
		
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	<p class="publicationTitle"> <strong>
            Accounting for variability in ion current recordings using a mathematical model of artefacts in voltage&#x2212;clamp experiments </strong> </p>
	    <p class="publicationAuthors"> <em> Chon Lok Lei&#x201a; Michael Clerx&#x201a; Dominic G Whittaker&#x201a; David J Gavaghan&#x201a; Teun P de Boer and Gary R Mirams  </em> </p>
	
	<p class="publicationDetails"> 
        In <em>bioRxiv</em>.
        2020.
        </p>
	
        		<p class="publicationlinks"> <a
        
            		href="/publications/publication14097-abstract.html">
			Details <span class="sr-only" > about <em> Accounting for variability in ion current recordings using a mathematical model of artefacts in voltage&#x2212;clamp experiments  </em></span> </a> |
			<a href="/publications/publication14097.bib">
			BibTeX  <span class="sr-only" > data for <em> Accounting for variability in ion current recordings using a mathematical model of artefacts in voltage&#x2212;clamp experiments  </em></span>   </a>
			
			 | <a
		href="http://dx.doi.org/10.1101/2019.12.20.884353">
		DOI (10.1101/2019.12.20.884353)
		</a> 
					| <a href="https://doi.org/10.1101/2019.12.20.884353"> Link <span class="sr-only" > to <em> Accounting for variability in ion current recordings using a mathematical model of artefacts in voltage&#x2212;clamp experiments  </em></span> </a>
  				
		
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	<p class="publicationTitle"> <strong>
            Probabilistic Inference on Noisy Time Series (PINTS) </strong> </p>
	    <p class="publicationAuthors"> <em> Michael Clerx&#x201a; Martin Robinson&#x201a; Ben Lambert&#x201a; Chon Lok Lei&#x201a; Sanmitra Ghosh&#x201a; Gary R Mirams and David J Gavaghan  </em> </p>
	
	<p class="publicationDetails"> 
        In <em>Journal of Open Research Software</em>.
        
            Vol. 7.
        
            No. 1.
        2019.
        </p>
	
        		<p class="publicationlinks"> <a
        
            		href="/publications/publication14099-abstract.html">
			Details <span class="sr-only" > about <em> Probabilistic Inference on Noisy Time Series (PINTS)  </em></span> </a> |
			<a href="/publications/publication14099.bib">
			BibTeX  <span class="sr-only" > data for <em> Probabilistic Inference on Noisy Time Series (PINTS)  </em></span>   </a>
			
			 | <a
		href="http://dx.doi.org/10.5334/jors.252">
		DOI (10.5334/jors.252)
		</a> 
					| <a href="https://doi.org/10.5334/jors.252"> Link <span class="sr-only" > to <em> Probabilistic Inference on Noisy Time Series (PINTS)  </em></span> </a>
  				
		
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	<p class="publicationTitle"> <strong>
            Rapid Characterization of hERG Channel Kinetics II: Temperature Dependence </strong> </p>
	    <p class="publicationAuthors"> <em> Chon Lok Lei&#x201a; Michael Clerx&#x201a; Kylie A. Beattie&#x201a; Dario Melgari&#x201a; Jules C. Hancox&#x201a; David J. Gavaghan&#x201a; Liudmila Polonchuk&#x201a; Ken Wang and Gary R. Mirams  </em> </p>
	
	<p class="publicationDetails"> 
        In <em>Biophysical Journal</em>.
        
            Vol. 117.
        
            No. 12.
        
                Pages 2455 &#x2212; 2470.
            2019.
        </p>
	
        		<p class="publicationlinks"> <a
        
            		href="/publications/publication13784-abstract.html">
			Details <span class="sr-only" > about <em> Rapid Characterization of hERG Channel Kinetics II: Temperature Dependence  </em></span> </a> |
			<a href="/publications/publication13784.bib">
			BibTeX  <span class="sr-only" > data for <em> Rapid Characterization of hERG Channel Kinetics II: Temperature Dependence  </em></span>   </a>
			
			 | <a
		href="http://dx.doi.org/https://doi.org/10.1016/j.bpj.2019.07.030">
		DOI (https://doi.org/10.1016/j.bpj.2019.07.030)
		</a> 
					| <a href="http://www.sciencedirect.com/science/article/pii/S0006349519305983"> Link <span class="sr-only" > to <em> Rapid Characterization of hERG Channel Kinetics II: Temperature Dependence  </em></span> </a>
  				
		
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	<p class="publicationTitle"> <strong>
            Rapid Characterization of hERG Channel Kinetics I: Using an Automated High&#x2212;Throughput System </strong> </p>
	    <p class="publicationAuthors"> <em> Chon Lok Lei&#x201a; Michael Clerx&#x201a; David J. Gavaghan&#x201a; Liudmila Polonchuk&#x201a; Gary R. Mirams and Ken Wang  </em> </p>
	
	<p class="publicationDetails"> 
        In <em>Biophysical Journal</em>.
        
            Vol. 117.
        
            No. 12.
        
                Pages 2438 &#x2212; 2454.
            2019.
        </p>
	
        		<p class="publicationlinks"> <a
        
            		href="/publications/publication13783-abstract.html">
			Details <span class="sr-only" > about <em> Rapid Characterization of hERG Channel Kinetics I: Using an Automated High&#x2212;Throughput System  </em></span> </a> |
			<a href="/publications/publication13783.bib">
			BibTeX  <span class="sr-only" > data for <em> Rapid Characterization of hERG Channel Kinetics I: Using an Automated High&#x2212;Throughput System  </em></span>   </a>
			
			 | <a
		href="http://dx.doi.org/https://doi.org/10.1016/j.bpj.2019.07.029">
		DOI (https://doi.org/10.1016/j.bpj.2019.07.029)
		</a> 
					| <a href="http://www.sciencedirect.com/science/article/pii/S0006349519305971"> Link <span class="sr-only" > to <em> Rapid Characterization of hERG Channel Kinetics I: Using an Automated High&#x2212;Throughput System  </em></span> </a>
  				
		
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	<p class="publicationTitle"> <strong>
            Beta&#x2212;cell hubs maintain Ca2+ oscillations in human and mouse islet simulations </strong> </p>
	    <p class="publicationAuthors"> <em> Chon&#x2212;Lok Lei&#x201a; Joely A Kellard&#x201a; Manami Hara&#x201a; James D Johnson&#x201a; Blanca Rodriguez and Linford JB Briant  </em> </p>
	
	<p class="publicationDetails"> 
        In <em>Islets</em>.
        
            Vol. 10.
        
            No. 4.
        
                Pages 151&#x2013;167.
            2018.
        </p>
	
        		<p class="publicationlinks"> <a
        
            		href="/publications/publication14098-abstract.html">
			Details <span class="sr-only" > about <em> Beta&#x2212;cell hubs maintain Ca2+ oscillations in human and mouse islet simulations  </em></span> </a> |
			<a href="/publications/publication14098.bib">
			BibTeX  <span class="sr-only" > data for <em> Beta&#x2212;cell hubs maintain Ca2+ oscillations in human and mouse islet simulations  </em></span>   </a>
			
			 | <a
		href="http://dx.doi.org/10.1080/19382014.2018.1493316">
		DOI (10.1080/19382014.2018.1493316)
		</a> 
					| <a href="https://doi.org/10.1080/19382014.2018.1493316"> Link <span class="sr-only" > to <em> Beta&#x2212;cell hubs maintain Ca2+ oscillations in human and mouse islet simulations  </em></span> </a>
  				
		
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	<p class="publicationTitle"> <strong>
            Tailoring mathematical models to stem&#x2212;cell derived cardiomyocyte lines can improve predictions of drug&#x2212;induced changes to their electrophysiology </strong> </p>
	    <p class="publicationAuthors"> <em> Chon Lok Lei&#x201a; Ken Wang&#x201a; Michael Clerx&#x201a; Ross H Johnstone&#x201a; Maria P Hortigon&#x2212;Vinagre&#x201a; Victor Zamora&#x201a; Andrew Allan&#x201a; Godfrey L Smith&#x201a; David J Gavaghan&#x201a; Gary R Mirams and others  </em> </p>
	
	<p class="publicationDetails"> 
        In <em>Frontiers in physiology</em>.
        
            Vol. 8.
        
                Pages 986.
            2017.
        </p>
	
        		<p class="publicationlinks"> <a
        
            		href="/publications/publication13782-abstract.html">
			Details <span class="sr-only" > about <em> Tailoring mathematical models to stem&#x2212;cell derived cardiomyocyte lines can improve predictions of drug&#x2212;induced changes to their electrophysiology  </em></span> </a> |
			<a href="/publications/publication13782.bib">
			BibTeX  <span class="sr-only" > data for <em> Tailoring mathematical models to stem&#x2212;cell derived cardiomyocyte lines can improve predictions of drug&#x2212;induced changes to their electrophysiology  </em></span>   </a>
			
			 | <a
		href="http://dx.doi.org/https://doi.org/10.3389/fphys.2017.00986">
		DOI (https://doi.org/10.3389/fphys.2017.00986)
		</a> 
					| <a href="https://www.frontiersin.org/articles/10.3389/fphys.2017.00986/full"> Link <span class="sr-only" > to <em> Tailoring mathematical models to stem&#x2212;cell derived cardiomyocyte lines can improve predictions of drug&#x2212;induced changes to their electrophysiology  </em></span> </a>
  				
		
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